SYNPO

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Mammalian protein found in Homo sapiens

title: "SYNPO" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public description: "Mammalian protein found in Homo sapiens" topic_path: "uncategorized" source: "https://en.wikipedia.org/wiki/SYNPO" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Mammalian protein found in Homo sapiens ::

Synaptopodin is a protein that in humans is encoded by the SYNPO gene.

Function

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997).[supplied by OMIM]

Interactions

SYNPO has been shown to interact with MAGI1.

References

References

  1. (Oct 1997). "Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes". The Journal of Cell Biology.
  2. (Jun 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research.
  3. "Entrez Gene: SYNPO synaptopodin".
  4. (Aug 2002). "Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1". The Journal of Biological Chemistry.

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