Steven E. Brenner
American biologist and academic
title: "Steven E. Brenner" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["university-of-california,-berkeley-college-of-letters-and-science-faculty", "american-bioinformaticians", "living-people", "21st-century-american-biologists", "overton-prize-winners", "harvard-university-alumni", "alumni-of-the-university-of-cambridge", "fellows-of-the-international-society-for-computational-biology", "year-of-birth-missing-(living-people)", "uc-berkeley-college-of-engineering-faculty"] description: "American biologist and academic" topic_path: "science/biology" source: "https://en.wikipedia.org/wiki/Steven_E._Brenner" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::summary American biologist and academic ::
::data[format=table title="Infobox scientist"]
| Field | Value |
|---|---|
| name | Steven Brenner |
| birth_name | Steven Elliot Brenner |
| image | File:Steven E. Brenner ISMB 2015.jpg |
| caption | Steven E. Brenner speaking at the ISMB conference in 2015. |
| birth_date | |
| death_date | |
| workplaces | {{Plainlist |
| alma_mater | {{Plainlist |
| doctoral_advisor | Cyrus Chothia |
| thesis_title | Molecular propinquity: evolutionary and structural relationships of proteins |
| thesis_url | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596888 |
| thesis_year | 1996 |
| known_for | Structural Classification of Proteins |
| awards | Overton Prize (2010) |
| signature | |
| website | |
| :: |
| name = Steven Brenner | birth_name = Steven Elliot Brenner | image = File:Steven E. Brenner ISMB 2015.jpg | image_size = | alt = | caption = Steven E. Brenner speaking at the ISMB conference in 2015. | birth_date = | birth_place = | death_date = | death_place = | residence = | citizenship = | nationality = | fields = | workplaces = {{Plainlist|
- University of California, Berkeley
- Laboratory of Molecular Biology, Cambridge}} | alma_mater = {{Plainlist|
- Harvard University (BS)
- University of Cambridge (PhD)}} | doctoral_advisor = Cyrus Chothia | thesis_title = Molecular propinquity: evolutionary and structural relationships of proteins | thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596888 | thesis_year = 1996 | academic_advisors = | doctoral_students = | notable_students = | known_for = Structural Classification of Proteins | influences = | influenced = | awards = Overton Prize (2010) | signature = | signature_alt = | footnotes = | spouse = | website =
Steven Elliot Brenner is a professor at the Department of Plant and Microbial Biology at the University of California Berkeley, adjunct professor at the Department of Bioengineering and Therapeutic Sciences at the University of California, and San Francisco Faculty scientist, Physical Biosciences at the Lawrence Berkeley National Laboratory.{{Cite journal | last1 = Stajich | first1 = J. E. | last2 = Block | first2 = D. | last3 = Boulez | first3 = K. | last4 = Brenner | first4 = S. | author-link4 = Steven E. Brenner | last5 = Chervitz | first5 = S. | last6 = Dagdigian | first6 = C. | last7 = Fuellen | first7 = G. | last8 = Gilbert | first8 = J. | last9 = Korf | first9 = I. | last10 = Lapp | first10 = H. | last11 = Lehväslaiho | first11 = H. | last12 = Matsalla | first12 = C. | last13 = Mungall | first13 = C. J. | last14 = Osborne | first14 = B. I. | last15 = Pocock | first15 = M. R. | last16 = Schattner | first16 = P. | last17 = Senger | first17 = M. | last18 = Stein | first18 = L. D. | author-link18 = Lincoln Stein | last19 = Stupka | first19 = E. | last20 = Wilkinson | first20 = M. D. | last21 = Birney | first21 = E. | author-link21 = Ewan Birney | title = The BioPerl Toolkit: Perl Modules for the Life Sciences | doi = 10.1101/gr.361602 | journal = Genome Research | volume = 12 | issue = 10 | pages = 1611–1618 | year = 2002 | pmid = 12368254 | pmc =187536
Education
Brenner gained his Bachelor of Arts in 1992 from Harvard University and Doctor of Philosophy in 1997 from the University of Cambridge for research supervised by Cyrus Chothia.{{cite thesis|degree=PhD |first=Steven Elliot |last=Brenner |title=Molecular propinquity: evolutionary and structural relationships of proteins |publisher=University of Cambridge |date=1996 |id=|url=http://ulmss-newton.lib.cam.ac.uk/vwebv/holdingsInfo?bibId=17617|website=lib.cam.ac.uk|oclc=879392272}} He was one of the creators of the Structural Classification of Proteins (SCOP) database{{Cite journal |last1 = Murzin |first1 = A. G. |last2 = Brenner |first2 = S. |author-link2 = Steven E. Brenner |last3 = Hubbard |first3 = T. |author-link3 = Tim Hubbard |last4 = Chothia |first4 = C. |author-link4 = Cyrus Chothia |title = SCOP: A structural classification of proteins database for the investigation of sequences and structures |journal = Journal of Molecular Biology |volume = 247 |issue = 4 |pages = 536–540 |year = 1995 |doi = 10.1016/S0022-2836(05)80134-2 |pmid = 7723011 |url = http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf |archive-url = https://web.archive.org/web/20120426170732/http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf |archive-date = 2012-04-26
Career and research
research in Brenner's laboratory investigates:
- Individual genome interpretation
- The regulation of gene expression by alternative splicing and nonsense-mediated decay of messenger RNA
- Protein function prediction using Bayesian phylogenomics
Awards and honors
In 2010 he was awarded the Overton Prize from the International Society for Computational Biology.
References
References
- (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". [[PLOS Computational Biology]].
- Brenner, Steven. (2017). "Brenner Laboratory: Computational Genomics Research Group".
- (2013). "Be prepared for the big genome leak: It is only a matter of time until idealism sees the release of confidential genetic data on study participants". Nature.
- "About Steven E. Brenner".
- "Overton Prize winners".
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