PPP5C

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Enzyme

title: "PPP5C" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["genes-mutated-in-mice"] description: "Enzyme" topic_path: "general/genes-mutated-in-mice" source: "https://en.wikipedia.org/wiki/PPP5C" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Enzyme ::

Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.

Interactions

PPP5C has been shown to interact with ASK1, CRY2 GNA12. and Rac1,

References

References

  1. (Sep 1995). "Cloning of a highly conserved human protein serine-threonine phosphatase gene from the glioma candidate region on chromosome 19q13.3". Genomics.
  2. "Entrez Gene: PPP5C Protein phosphatase 5, catalytic subunit".
  3. (Nov 2001). "Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress". The EMBO Journal.
  4. (Nov 1997). "Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity". Photochemistry and Photobiology.
  5. (Aug 2002). "Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity". Current Biology.
  6. (Feb 2010). "Activated Rac1 GTPase translocates protein phosphatase 5 to the cell membrane and stimulates phosphatase activity in vitro". The Journal of Biological Chemistry.

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