Pinin

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Protein-coding gene in the species Homo sapiens

title: "Pinin" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public description: "Protein-coding gene in the species Homo sapiens" topic_path: "uncategorized" source: "https://en.wikipedia.org/wiki/Pinin" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Protein-coding gene in the species Homo sapiens ::

Pinin is a protein that in humans is encoded by the PNN gene.

Interactions

Pinin has been shown to interact with Keratin 8, Keratin 18, RNPS1, PRPF4B, SFRS4, PPIG, SRRM2 and SFRS18.

References

References

  1. (January 1997). "Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex". J Cell Biol.
  2. "Entrez Gene: PNN pinin, desmosome associated protein".
  3. Shi, J. (May 2000). "Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus". J. Biol. Chem..
  4. Alpatov, Roman. (December 2004). "Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene". Mol. Cell. Biol..
  5. Ewing, Rob M. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol..
  6. Li, Chin. (October 2003). "Nuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA processing and export via interaction with RNPS1". Mol. Cell. Biol..
  7. Dellaire, Graham. (July 2002). "Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes". Mol. Cell. Biol..
  8. Zimowska, Grazyna. (November 2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci..
  9. Lin, Chun Lun. (August 2004). "Over-expression of SR-cyclophilin, an interaction partner of nuclear pinin, releases SR family splicing factors from nuclear speckles". Biochem. Biophys. Res. Commun..

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