Mosapramine

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Column 1
Cremin (クレミン, JP)
International Drug Names
Oral (tablets, oral solution)
.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}N05AX10 (WHO)
Rx-only (JP)
IUPAC name
1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
89419-40-9 Y
4257
DB13676
4107
04UZQ7O9SJ
D08235 Y
DTXSID0048846
C28H35ClN4O
479.07 g·mol−1
Interactive image
SMILES
C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
InChI
InChI=1S/C28H35ClN4O/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34)Key:PXUIZULXJVRBPC-UHFFFAOYSA-N
.mw-parser-output .nobold{font-weight:normal}  (verify)

Mosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.

• Carpipramine
• Clocapramine
• Fluspirilene (typical antipsychotic)
• Imidazopyridine

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