Metfendrazine
Chemical compound
title: "Metfendrazine" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["abandoned-drugs", "methamphetamines", "monoamine-oxidase-inhibitors", "phenethylhydrazines"] description: "Chemical compound" topic_path: "arts/music" source: "https://en.wikipedia.org/wiki/Metfendrazine" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::summary Chemical compound ::
| image = Metfendrazine structure.svg | image_class = skin-invert-image | width = 200px
| tradename = | pregnancy_category = | legal_status = Uncontrolled | routes_of_administration = Oral
| bioavailability = | metabolism = | elimination_half-life = | excretion =
| CAS_number_Ref = | CAS_number = 3734-26-7 | UNII_Ref = | UNII = A52QTC656T | ATC_prefix = none | ATC_suffix = | PubChem = 19516 | ChemSpiderID = 18390 | synonyms = Methphendrazine; HM-11; MO-482; N-Aminomethamphetamine; Methamphetamine hydrazide; N-Amino-N-methylamphetamine
| IUPAC_name = 1-methyl-1-(1-methyl-2-phenyl-ethyl)hydrazine | C=10 | H=16 | N=2
Metfendrazine (developmental code names HM-11, MO-482), also known as methphendrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was investigated as an antidepressant, but was never marketed.
Chemistry
Metfendrazine, also known as methamphetamine hydrazide, is a phenethylamine, amphetamine, and hydrazine derivative.
It is an analogue and derivative of phenelzine (phenethylamine hydrazide) and pheniprazine (amphetamine hydrazide), as well as of phenethylamine, amphetamine, and methamphetamine.
References
References
- (1962). "Metfendrazine, a new inhibitor of monoamine oxidase". Archivos del Instituto de Farmacología Experimental.
- (October 1960). "A comparison of perphenazine, proketazine, nialamide and MO-482 in chronic schizophrenics". The American Journal of Psychiatry.
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