M320 (opioid)

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Column 1
(5α,6β,14β,18R)-17-(Cyclopropylmethyl)-18-[(2R)-2-hydroxy-5-methyl-2-hexanyl]-6-methoxy-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol
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UK: Under Psychoactive Substances Act
IUPAC name
(1R,2S,6R,14R,15R,19R)-5-(Cyclopropylmethyl)-19-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
71717732
29420445
ChEMBL2338714
C30H41NO4
479.661 g·mol−1
Interactive image
SMILES
CC(C)CCC@([C@H]1C[C@@]23C=C[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
InChI
InChI=1S/C30H41NO4/c1-18(2)9-10-27(3,33)22-16-28-11-12-30(22,34-4)26-29(28)13-14-31(17-19-5-6-19)23(28)15-20-7-8-21(32)25(35-26)24(20)29/h7-8,11-12,18-19,22-23,26,32-33H,5-6,9-10,13-17H2,1-4H3/t22-,23-,26-,27-,28-,29+,30-/m1/s1Key:MFIWLPVODKSMKX-XELDOGJXSA-N

M320 is an extremely potent and long acting opioid. It produces long lasting narcosis in different animals, including mice, rats, cats, guinea pigs, dogs and monkeys. M320 is a μ and κ-opioid receptor agonist. Similarly to TL 2636, M320 tends to produce pronounced nausea and vomiting due to its potent agonist activity at both the μ and κ-opioid receptors at the same time.

• Bentley compounds
• BU72
• Carfentanil
• Etonitazene
• Etorphine (M99)
• Fentanyl
• TH-030418

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