Ligneous conjunctivitis
title: "Ligneous conjunctivitis" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["disorders-of-conjunctiva", "inflammations", "igg4-related-disease"] topic_path: "general/disorders-of-conjunctiva" source: "https://en.wikipedia.org/wiki/Ligneous_conjunctivitis" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::data[format=table title="Infobox medical condition (new)"]
| Field | Value |
|---|---|
| name | Ligneous conjunctivitis |
| synonyms | Conjunctivitis lignosa |
| field | ophthalmology |
| :: |
| name = Ligneous conjunctivitis | synonyms = Conjunctivitis lignosa | image = | alt = | caption = | pronounce = | field = ophthalmology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = Ligneous conjunctivitis is a rare form of chronic conjunctivitis characterized by recurrent, fibrin-rich pseudomembranous lesions of wood-like consistency that develop mainly on the underside of the eyelid (tarsal conjunctiva). It is generally a systemic disease which may involve the periodontal tissue, the upper and lower respiratory tract, kidneys, middle ear, and female genitalia. It can be sight-threatening, and death can occasionally occur from pulmonary involvement.
It has been speculated hola ligneous conjunctivitis may be a manifestation of IgG4-related disease (IgG4-RD) involving the conjunctiva.
Presentation
Pathogenesis
Histopathological findings from affected humans indicate that wound healing is impaired due to a deficiency in plasmin-mediated extracellular fibrinolysis. Episodes may be triggered by minor trauma, eye surgery, or by systemic events such as infections or antifibrinolytic therapy. Histology shows amorphous subepithelial deposits of eosinophilic material consisting predominantly of fibrin.
Treatment
Ligneous conjunctivitis may be managed by topical treatments of plasminogen,
References
References
- "Orphanet: Ligneous conjunctivitis".
- (2003). "Ligneous conjunctivitis". Survey of Ophthalmology.
- "Ligneous conjunctivitis". Orphanet.
- (9 September 2016). "Co-existing ligneous conjunctivitis and IgG4-related disease". [[Indian Journal of Ophthalmology]].
- "Ligneous Conjunctivitis". Ocular Pathology.
::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::