JWH-398

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Column 1
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CA: Schedule II
DE: NpSG (Industrial and scientific use only)
UK: Class B
US: Schedule I
Illegal in Latvia
IUPAC name
1-Pentyl-3-(4-chloro-1-naphthoyl)indole
1292765-18-4 N
28647395 N
RX0E95S90H
DTXSID40156131
C24H22ClNO
375.90 g·mol−1
Interactive image
SMILES
c14ccccc1n(CCCCC)cc4C(=O)c(cc3)c2ccccc2c3Cl
InChI
InChI=1S/C24H22ClNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 NKey:IUWBHGFOHXVVKV-UHFFFAOYSA-N N
.mw-parser-output .nobold{font-weight:normal} NY (what is this?)  (verify)

JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It has mild selectivity for CB1 with a Ki of 2.3 nM and 2.8 nM at CB2. This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate "herbal incense" products purchased from online shops between February and June 2009. It was discovered by, and named after, John W. Huffman.

In the United States, JWH-398 is a Schedule I controlled substance.

• 5F-JWH-398
• JWH-122
• JWH-424

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