HLA-DR6

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Broad-antigen serotype

title: "HLA-DR6" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["hla-dr-haplotypes"] description: "Broad-antigen serotype" topic_path: "general/hla-dr-haplotypes" source: "https://en.wikipedia.org/wiki/HLA-DR6" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Broad-antigen serotype ::

::figure[src="https://upload.wikimedia.org/wikipedia/commons/0/0d/DR_Illustration.PNG" caption="'''Illustration of HLA-DR'''"] ::

HLA-DR6 (DR6) is a broad-antigen serotype that is further split into HLA-DR13 and HLA-DR14 antigen serotypes.

Serology

DR6 serological reactivity is relatively poor compared to other serological tests for DR antigens. Compare to DQ2 or DR7.

Disease associations

DR13 and DR14 share a common association to myasthenia gravis.

Allele groups

HLA-DRB113 and HLA-DRB114 encode serotypes of DR6.

References

References

  1. [http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]
  2. DR12 - 3%, DR11 - 3% DR5-2%
  3. DR12 - 6%, DR11 - 7% DR5-4%
  4. DR1404 - 3%
  5. DR4 - 25%
  6. (2004). "A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan.". Clin Immunol.

::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::

hla-dr-haplotypes