HLA-B8

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title: "HLA-B8" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["hla-b-alleles"] description: "Human leukocyte antigen serotype" topic_path: "general/hla-b-alleles" source: "https://en.wikipedia.org/wiki/HLA-B8" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Human leukocyte antigen serotype ::

HLA-B8 (B8) is an HLA-B serotype. The serotype identifies the HLA-B*08 gene products. (For terminology help see: HLA-serotype tutorial) HLA-B8, previously known as HL-A8 was one of the first identified of the HLA antigens. It coined the "Super B8" haplotype, also called the ancestral European haplotype because of its common occurrence in Europe, particular the isles and Scandinavia. B8 is a component gene-allele of the AH8.1 haplotype in Northern and Western Europeans. Genes between B8 and DR3 on this haplotype are frequently associated with autoimmune disease.

Serotype

::data[format=table title="B8 serotype recognition of Some HLA B*08 allele-group gene products[http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]"]

Allele links out to IMGT/HLA Databease at EBI
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Alleles

::data[format=table title="'''HLA B*0801 frequencies'''"]

	Taiwan Siraya	1.0
::

References

References

1. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens.
2. [http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]
3. (2003). "New allele frequency database". Tissue Antigens.

::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::