GTF2F1
Protein-coding gene in the species Homo sapiens
title: "GTF2F1" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["transcription-factors"] description: "Protein-coding gene in the species Homo sapiens" topic_path: "arts/film" source: "https://en.wikipedia.org/wiki/GTF2F1" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::summary Protein-coding gene in the species Homo sapiens ::
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.
Interactions
GTF2F1 has been shown to interact with:
- CTDP1,
- GTF2H4,
- HNRPU,
- MED21,
- POLR2A,
- Serum response factor
- TAF11,
- TAF1,
- TATA binding protein, and
- Transcription Factor II B.
References
References
- (March 1992). "A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II". Nature.
- "Entrez Gene: GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa".
- (October 1998). "FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO". J. Biol. Chem..
- (May 1997). "BRCA1 is a component of the RNA polymerase II holoenzyme". Proc. Natl. Acad. Sci. U.S.A..
- (October 1999). "hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation". Mol. Cell. Biol..
- (October 1997). "CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription". Mol. Cell. Biol..
- (February 1995). "Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor". Nature.
- (February 1994). "Role of transcription factor TFIIF in serum response factor-activated transcription". J. Biol. Chem..
- (March 1996). "TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74". Cell.
- (November 1995). "Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation". Genes Dev..
- (January 1999). "Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250". Mol. Cell. Biol..
- (March 1998). "A dynamic model for PC4 coactivator function in RNA polymerase II transcription". Proc. Natl. Acad. Sci. U.S.A..
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