GNAI1

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Protein-coding gene in humans

title: "GNAI1" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public description: "Protein-coding gene in humans" topic_path: "uncategorized" source: "https://en.wikipedia.org/wiki/GNAI1" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Protein-coding gene in humans ::

Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.

Interactive pathway map

Interactions

GNAI1 has been shown to interact with:

References

References

  1. (Aug 1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proceedings of the National Academy of Sciences of the United States of America.
  2. "Entrez Gene: GNAI1 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1".
  3. (Sep 1999). "Ocular albinism: evidence for a defect in an intracellular signal transduction system". Nature Genetics.
  4. (Aug 2001). "RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity". The Journal of Biological Chemistry.
  5. (Apr 2002). "Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits". Nature.
  6. (Jun 1999). "Structural basis for the selectivity of the RGS protein, GAIP, for Galphai family members. Identification of a single amino acid determinant for selective interaction of Galphai subunits with GAIP". The Journal of Biological Chemistry.
  7. (Dec 1996). "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits". Proceedings of the National Academy of Sciences of the United States of America.
  8. (Mar 2003). "Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". The Journal of Biological Chemistry.
  9. (May 1996). "The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway". The Journal of Biological Chemistry.

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