Fustin


title: "Fustin" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["flavanonols", "catechols"] topic_path: "general/flavanonols" source: "https://en.wikipedia.org/wiki/Fustin" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

| Watchedfields = changed | verifiedrevid = 424693354 | Name = Fustin | ImageFile = Fustin.svg | ImageSize = 200px | IUPACName = (2R,3R)-3,3′,4′,7-Tetrahydroxyflavan-4-one | SystematicName = (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one | OtherNames = 2,3-Dihydrofisetin 3,7,3',4'-Tetrahydroxyflavanone 2,3-Dihydrofisetin 3′,4′,7-Trihydroxyflavanol |Section1={{Chembox Identifiers | CASNo_Ref = | CASNo = 20725-03-5 | ChEBI = 5202 | ChEMBL = 470267 | ChemSpiderID = 4476304 | EINECS = 243-989-6 | KEGG = C01378 | UNII_Ref = | UNII = 4994C1X19A | PubChem = 5317435 | StdInChI=1S/C15H12O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,14-18,20H/t14-,15+/m0/s1 | StdInChIKey = FNUPUYFWZXZMIE-LSDHHAIUSA-N | SMILES = C1=CC(=C(C=C1[C@@H]2C@HO)O)O |Section2={{Chembox Properties | C=15|H=12|O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt =

Fustin, sometimes called "dihydrofisetin", is a flavanonol, a type of flavonoid. It can be found in young fustic (Cotinus coggygria) and in the lacquer tree (Toxicodendron vernicifluum).

Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.

Unlike fisetin, fustin has no double bond in the C-ring. This makes fustin a flavan, with two stereocenters and four stereoisomers.

References

References

  1. (2009). "Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles". Analytical and Bioanalytical Chemistry.
  2. (2007). "Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death". Experimental & Molecular Medicine.

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