Fustin

title: "Fustin" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["flavanonols", "catechols"] topic_path: "general/flavanonols" source: "https://en.wikipedia.org/wiki/Fustin" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
| Watchedfields = changed | verifiedrevid = 424693354 | Name = Fustin | ImageFile = Fustin.svg | ImageSize = 200px | IUPACName = (2R,3R)-3,3′,4′,7-Tetrahydroxyflavan-4-one | SystematicName = (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one | OtherNames = 2,3-Dihydrofisetin 3,7,3',4'-Tetrahydroxyflavanone 2,3-Dihydrofisetin 3′,4′,7-Trihydroxyflavanol |Section1={{Chembox Identifiers | CASNo_Ref = | CASNo = 20725-03-5 | ChEBI = 5202 | ChEMBL = 470267 | ChemSpiderID = 4476304 | EINECS = 243-989-6 | KEGG = C01378 | UNII_Ref = | UNII = 4994C1X19A | PubChem = 5317435 | StdInChI=1S/C15H12O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,14-18,20H/t14-,15+/m0/s1 | StdInChIKey = FNUPUYFWZXZMIE-LSDHHAIUSA-N | SMILES = C1=CC(=C(C=C1[C@@H]2C@HO)O)O |Section2={{Chembox Properties | C=15|H=12|O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt =
Fustin, sometimes called "dihydrofisetin", is a flavanonol, a type of flavonoid. It can be found in young fustic (Cotinus coggygria) and in the lacquer tree (Toxicodendron vernicifluum).
Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
Unlike fisetin, fustin has no double bond in the C-ring. This makes fustin a flavan, with two stereocenters and four stereoisomers.
References
References
- (2009). "Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles". Analytical and Bioanalytical Chemistry.
- (2007). "Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death". Experimental & Molecular Medicine.
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