Fortrea

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Contract research organization

title: "Fortrea" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["2015-mergers-and-acquisitions", "animal-testing-in-the-united-states", "companies-based-in-durham,-north-carolina", "companies-formerly-listed-on-the-new-york-stock-exchange", "companies-listed-on-the-nasdaq", "contract-research-organizations", "corning-inc.", "corporate-spin-offs"] description: "Contract research organization" topic_path: "geography/united-states" source: "https://en.wikipedia.org/wiki/Fortrea" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Contract research organization ::

::data[format=table title="Infobox company"]

FieldValue
nameFortrea Holdings Inc.
typePublic
traded_as
industryPharmaceutical industry
founded1968 as Environmental Sciences Corporation1996 as Covance as Fortrea
hq_locationDurham, North Carolina, U.S.; operations in over 90 countries
key_people
servicesContract research organization
revenue
operating_income
net_income
assets
equity
num_employeesApproximately 15,500 (2024)
website
footnotes
::

| name = Fortrea Holdings Inc. | logo = | type = Public | traded_as = | industry = Pharmaceutical industry | founded = 1968 as Environmental Sciences Corporation1996 as Covance as Fortrea | hq_location = Durham, North Carolina, U.S.; operations in over 90 countries | key_people = | services = Contract research organization | revenue = | operating_income = | net_income = | assets = | equity = | num_employees = Approximately 15,500 (2024) | website = | footnotes =

Fortrea Holdings Inc. is an American contract research organization organized in Delaware and headquartered in Durham, North Carolina with operations in 90 countries. Its customers are primarily in the pharmaceutical, biotechnology, and medical device industries.

Its primary business is handling all aspects of clinical trials including phase I through IV clinical trial management, clinical pharmacology, and post-approval services. It handles regulatory affairs, protocol design, operational planning, study and site start-up, patient recruitment, project management, monitoring, data management and biostatistics, pharmacovigilance, medical writing, and mobile clinical services. It focuses on oncology, central nervous system and neurodegenerative, rare diseases, and cell and gene therapies. In the five years ending in 2023, it conducted more than 5,850 clinical trials involving over 1 million subjects. It also conducted over 600 studies for medical device companies.

The company is one of the largest participants in the international primate trade and has been criticized for its animal testing practices, most specifically animal testing on non-human primates.

The company traces its roots to Environmental Sciences Corporation, formed in 1968. It was known as Hazleton from 1972 to 1990, Corning Lab Services from 1990 to 1996, Covance from 1996 to 2021, and Labcorp Drug Development from 2021 to 2023.

History

1968–1999

In 1968, Environmental Sciences Corporation was established in Seattle, Washington, manufacturing equipment related to laboratory animals. In 1972, it acquired and took the name of Hazleton Laboratories, a contract laboratory that conducted toxicology testing. By 1982, Hazleton was the largest independent biological testing company and life sciences laboratory in the U.S. and the largest laboratory equipment manufacturer worldwide. The company carried out animal toxicology tests of drugs, cosmetics, pesticides, and industrial chemicals, and bred rhesus monkeys and beagles for its own labs, as well as for chemical and drug companies, hospitals, universities and government agencies. It offered chemical analysis of new compound products for various industries, tested chemicals for gene mutations, and carried out research with monoclonal antibodies. It sold the equipment manufacturing unit in the mid-1980s.

In 1989, Corning Glass Works acquired G.H. Besselaar Associates, which conducted clinical trials for drug approvals. In 1990, Hazleton acquired Microtest, a molecular toxicology center in York, England.

In 1992, it acquired Philadelphia Association of Clinical Trials. In 1993, Hazleton, Besselaar, and SciCor were combined into Corning Pharmaceutical Services, then Corning Life Sciences.

In 1995, Corning Pharmaceutical Services acquired National Packaging Systems, an Allentown, Pennsylvania-based clinical trial packaging company.

In 1997, Corning completed the corporate spin-off of its laboratory testing business as Quest Diagnostics and its pharmaceutical services business as Covance.

In the fourth quarter of 1998, the company acquired GDXI, which undertakes the capture and interpretation of electrocardiograms, and Berkeley Antibody Company, which provides contract services in custom antibody production, applied immunology, and custom animal testing to support the medical device industry and preclinical evaluations, for a total of $26 million in cash.

2000-present

In 2000, the company opened a central laboratory in Singapore, building on clinical-development services formed in Singapore in 1996. In 2013, it expanded the capacity of the laboratory by 50%.

In March 2001, the company sold Covance Pharmaceutical Packaging Services to Fisher Scientific for $137.5 million.

In August 2005, it acquired GFI Clinical Services, an 80-bed clinical pharmacology business, from West Pharmaceutical Services for $5.7 million.

In April 2006, the company acquired eight early phase clinical pharmacology sites from Radiant Research for $65 million.

In June 2006, it acquired Signet Laboratories, a provider of monoclonal antibodies used in the research of cancer, infectious disease, and neurodegenerative disease, for $8.95 million.

In 2007, the company opened a laboratory in Shanghai, China. In 2019, it opened a research and development center in Shanghai.

In August 2008, the company acquired a campus in Greenfield, Indiana from Eli Lilly and Company and executed a 10-year service drug development service agreement with Lilly.

In December 2008, the company acquired a minority equity stake in Caprion Proteomics, a provider of proteomics-based services to the pharmaceutical industry. The company was acquired by Chicago Growth Partners in July 2012.

In 2009, the company acquired the Gene Expression Laboratory from Merck & Co. and entered into a five-year, $145 million contract to provide Merck with genomic analysis services.

In 2010, the company and Sanofi-Aventis created an outsourcing partnership, which, at the time was considered the largest between a contract research organization and a pharmaceutical company. Covance also acquired sites from Sanofi-Aventis in Porcheville, France and Alnwick, United Kingdom.

In 2014, the company acquired Medaxial, a London-based value communication consultancy.

In February 2015, Labcorp acquired Covance for $6.1 billion in cash and stock.

In 2016, the company entered into a strategic alliance with Global Specimen Solutions, in which the company offered GSS products GlobalCODE and snapTRACK to its clients. In December 2017, Covance acquired the company.

In September 2017, the company acquired Chiltern, a specialty contract research organization, for $1.2 billion in cash.

In June 2018, the company acquired Sciformix Corporation, a scientific process outsourcing company focused on pharmacovigilance and regulatory issues for biopharmaceutical and medical devices clients.

In August 2018, Covance Food Solutions was sold to Eurofins Scientific for $670 million.

In June 2019, the company acquired the nonclinical contract research services business of Envigo (now Inotiv), which acquired the research products business of the company.

In the first quarter of 2019, the company spent $47 million to acquire MI Bioresearch, a provider of preclinical capabilities in cell and gene therapy and oncology testing, and Regulatory and Clinical Research Institute (RCRI), a device-focused contract research organization.

In October 2020, the company acquired GlobalCare, a mobile nursing and ambulant care company with operations in more than 65 countries, and snapIoT, a company that provides a digitized clinical platform that supports remote participation in clinical trials.

In June 2021, the company changed its name to Labcorp Drug Development.

In February 2023, the company was renamed Fortrea Holdings. In July 2023, Labcorp completed the corporate spin-off of the company.

In June 2024, the company sold its Endpoint Clinical and Fortrea Patient Access businesses to Arsenal Capital Partners.

Controversies

Reston virus: monkeys with ebola virus brought to U.S.

In December 1989, several crab-eating macaques with the Zaire ebolavirus were imported from Mindanao in the Philippines to the company's facility in Reston, Virginia. The strain of the virus became known as the Reston virus. It was the first ebola virus that emerged outside of Africa and was also the first known natural infection of ebola virus in nonhuman primates. The facility was abandoned and torn down and the variant turned out to be non-lethal to humans. The incident was an inspiration for The Hot Zone, a book by Richard Preston published in 1994.

In March 1996, two macaques that had been shipped to the company's facility in Alice, Texas, tested positive for the Ebola virus from a group of 100 obtained from the same supplier. The virus strain was the same non-lethal Reston virus as in the earlier incident.

Animal welfare issues

Reports from investigative journalists

In 2003, a German investigative journalist sponsored by the British Union for the Abolition of Vivisection (BUAV) filmed 40 hours of undercover footage at the company's primate-testing facility in Münster. Two films were produced, which were shown on German public television in December 2003. The footage showed animal keepers dancing with half-anaesthetized monkeys, making their heads move to the rhythm of the music. The company gained an injunction against the video.

From April 2004 to March 2005, an undercover technician, sponsored by People for the Ethical Treatment of Animals (PETA), filmed the treatment of monkeys in the company's lab in Vienna, Virginia. Incidents filmed included the punching of injured monkey, failure to give veterinary care and self-mutilation by monkeys because of "failure to provide psychological enrichment". The United States Department of Agriculture and the Food and Drug Administration investigated the claims and company agreed to a settlement of $8,720 and to fix the infractions. In June 2005, the company filed a lawsuit in the United States against PETA and the investigator for fraud, breach of employee contract, and conspiracy. PETA agreed to hand over all video footage and written notes to the company, and agreed to a ban on conducting any infiltration of the company for five years. The company then dropped the lawsuit.

Celebrity protests of business expansion

In 2006, Paul McCartney protested a proposed $175 million animal testing laboratory by the company in Chandler, Arizona. However, the laboratory opened in 2009.

Animal welfare citations by the United States Department of Agriculture

In June 2011, a report showed that improper housing conditions led to frostbite on the tails of many monkeys.

In February 2012, the company was cited after a monkey died after being entangled by an enrichment device.

In March 2012, the company was cited for housing a monkey in isolation for almost eight months.

Deaths of lab monkeys due to hyperthermia

The company was fined $31,500 for four violations of the Animal Welfare Act of 1966 after 13 cynomolgus monkeys died from hyperthermia in overheated rooms in September and October 2014. In July 2014, the company had transported monkeys to the facility without providing water or proper care and ignoring signs of weakness and distress. The company said it would add electronic temperature monitoring and alerts.

Broken bone injuries in monkeys

In November 2023, the company was fined $9,000 due to the injuries of six monkeys between 2018 and 2022, mostly broken bones due to poor handling. After the injuries, four monkeys were euthanized.

References

References

  1. (March 3, 2025). "Fortrea Holdings Inc. Form 10-K for the Fiscal Year Ended December 31, 2024". [[U.S. Securities and Exchange Commission]].
  2. "General Information Name Search". [[Delaware]].
  3. "Covance Inc.".
  4. (January 3, 1987). "COMPANY NEWS; Corning-Hazleton". [[The New York Times]].
  5. (December 26, 1988). "CORNING GLASS TO ACQUIRE G.H. BESSELAAR ASSOCIATES". [[The Journal of Commerce]].
  6. (January 2, 1997). "Corning Incorporated Completes Spin-off of Quest Diagnostics and Covance to Shareholders". [[Quest Diagnostics]].
  7. (November 28, 1996). "Corning to Spin Off 2 Subsidiaries to Shareholders". [[The New York Times]].
  8. (March 4, 1999). "Covance Inc. FORM 10-K for the Fiscal Year Ended December 31, 1998". [[U.S. Securities and Exchange Commission]].
  9. (March 13, 2001). "Covance Inc. FORM 10-K for the Fiscal Year Ended December 31, 2000". [[U.S. Securities and Exchange Commission]].
  10. (7 April 2006). "The opening of Covance (Asia) Pte Ltd's expanded central laboratory". [[Ministry of Health (Singapore).
  11. (April 16, 2013). "Covance Expands Singapore Central Laboratory by 50 Percent to Meet Clients' Increased Asia Pacific Focus". [[PR Newswire]].
  12. Garde, Damian. (April 16, 2013). "Covance Expands Singapore Central Laboratory by 50 Percent to Meet Clients' Increased Asia Pacific Focus". [[Questex]].
  13. (April 22, 2013). "CRO Covance Expands Laboratory In Singapore". [[Asian Scientist]].
  14. (March 2, 2001). "Fisher completes Covance deal". Manufacturing Chemist.
  15. (December 27, 2000). "COMPANY NEWS; FISHER SCIENTIFIC TO BUY PACKAGING UNIT OF COVANCE". [[The New York Times]].
  16. (December 26, 2000). "Fisher Scientific to Acquire Packaging Unit of Covance". [[The Wall Street Journal]].
  17. (August 23, 2005). "West Pharmaceutical Sells Evansville GFI Assets". [[WFIE]].
  18. (April 20, 2006). "Covance buys eight trial sites for $65M". [[Questex]].
  19. (April 20, 2006). "Covance to Increase Phase I/IIa Capacity With Acquisition of Eight Early Clinical Development Sites From Radiant Research". [[PR Newswire]].
  20. (June 1, 2006). "Radiant Research Completes Sale Of Clinical Pharmacology Business Unit For Approximately $65 Million". [[Business Wire]].
  21. (June 1, 2006). "Covance Inc. Expands Its Antibody Products And Services With The Acquisition Of Signet Laboratories, Inc. For $8.95 Million". [[PR Newswire]].
  22. (April 6, 2009). "Covance Inc. Central Laboratory Receives CAP Accreditation in China". [[PR Newswire]].
  23. (September 10, 2019). "Covance Unveils New R&D Center in Shanghai". [[Labcorp]].
  24. (August 6, 2008). "Lilly Sells its Greenfield, Indiana, Operations to Covance; Expands Existing Collaboration Between the Two Companies". [[Eli Lilly & Company]].
  25. (August 6, 2008). "Covance and Eli Lilly and Company Execute 10-Year, $1.6 Billion Services Contract; Covance to Acquire Lilly's Greenfield, Indian". [[Questex]].
  26. (December 16, 2008). "Covance Purchases Equity Stake in Caprion Proteomics". [[Questex]].
  27. (December 17, 2008). "Covance Purchases Equity Stake in Caprion Proteomics". [[Mary Ann Liebert]].
  28. "Chicago Caprion Proteomics completes sale to Chicago Growth Partners". [[McCarthy Tétrault]].
  29. Myers, Calisha. (August 10, 2009). "Covance to Acquire Seattle-Based Gene Expression Laboratory from Merck & Co., Inc.". [[Questex]].
  30. (December 16, 2008). "Covance Purchases Equity Stake in Caprion Proteomics". [[Questex]].
  31. (July 30, 2009). "Covance Takes Over Merck & Co.'s Gene-Expression Lab and Gains $145M Contract". [[Mary Ann Liebert]].
  32. Jack, Andrew. (October 1, 2010). "Sanofi-Aventis in $2.2bn deal with Covance". [[Financial Times]].
  33. Carroll, John. (September 30, 2010). "Sanofi ejects two R&D sites, forges $2.2B pact with Covance". [[Questex]].
  34. (September 30, 2010). "Sanofi-Aventis Sells Two CMC Sites to Covance for $25M in $1–2B Services Deal". [[Mary Ann Liebert]].
  35. Garde, Damian. (May 19, 2014). "Covance Acquires Medaxial". [[Questex]].
  36. (February 19, 2015). "LabCorp Completes Acquisition of Covance". [[Labcorp]].
  37. Covington, Owen. (February 19, 2015). "Covance purchase a done deal for LabCorp". [[American City Business Journals]].
  38. (October 13, 2016). "Global Specimen Solutions, Inc. Announces 5-Year Strategic Alliance with Covance". [[PR Web]].
  39. (February 22, 2018). "LABORATORY CORPORATION OF AMERICA HOLDINGS FORM 10-K for the Fiscal Year Ended December 31, 2017". [[U.S. Securities and Exchange Commission]].
  40. (September 1, 2017). "LabCorp Completes Acquisition of Chiltern". [[Labcorp]].
  41. Adams, Ben. (July 31, 2017). "LabCorp snaps up Chiltern in $1.2B cash buy". [[Questex]].
  42. (July 31, 2017). "LabCorp Acquires Chiltern, Evotec Buys Aptuit as CROs Consolidate Further". [[Mary Ann Liebert]].
  43. (June 11, 2018). "LabCorp Expands Drug Development Solutions with Acquisition of Sciformix". [[Labcorp]].
  44. Hale, Conor. (June 11, 2018). "LabCorp acquires Sciformix to add postmarket services to Covance's portfolio". [[Questex]].
  45. Seaman, Jessica. (June 11, 2018). "LabCorp makes another acquisition to expand its drug development services". [[American City Business Journals]].
  46. Joyce, John. (August 2, 2018). "LabCorp completes $670M sale of Covance Food Solutions". [[American City Business Journals]].
  47. (August 2, 2018). "Eurofins Announces the Acquisition of Covance Food Solutions". [[Eurofins Scientific]].
  48. (April 30, 2018). "Labcorp Enters into Definitive Agreement to Sell Covance Food Solutions to Eurofins for $670 Million". [[Business Wire]].
  49. (June 3, 2019). "LabCorp and Envigo Complete Innovative Transactions". [[Labcorp]].
  50. Adams, Ben. (April 25, 2019). "LabCorp spends $485M as its CRO unit snaps up Envigo's nonclinical business". [[Questex]].
  51. (2019). "MI Bioresearch has been sold to Covance, a subsidiary of LabCorp". [[Lincoln International]].
  52. Adams, Ben. (January 21, 2020). "LabCorp's CRO unit Covance doubles down on cell, gene therapy offerings". [[Questex]].
  53. (October 20, 2020). "LabCorp Transforms the Clinical Trial Experience And Streamlines the Drug Development Process". [[Business Wire]].
  54. Cadman, Nola. (June 8, 2021). "Covance will soon be Labcorp Drug Development".
  55. Keenan, Joseph. (February 16, 2023). "Labcorp's spinoff CRO business gets a name—Fortrea". [[Questex]].
  56. (July 3, 2023). "Labcorp Completes Spin-off of Fortrea". [[PR Newswire]].
  57. (June 4, 2024). "Fortrea Completes Divestiture of Endpoint Clinical and Patient Access Businesses to Arsenal Capital Partners". [[Globe Newswire]].
  58. (December 3, 1989). "Deadly Virus Discovered in Laboratory Monkeys". [[The New York Times]].
  59. Cohn, D'Vera. (December 1, 1989). "Deadly Ebola Virus Found In Va. Laboratory Monkey;Animals Sent to Reston From Philippines". [[The Washington Post]].
  60. (November 1, 2011). "Reston ebolavirus in Humans and Animals in the Philippines: A Review". [[The Journal of Infectious Diseases]].
  61. (August 10, 2014). "25 years ago in Virginia, a very different Ebola outbreak". [[CBS News]].
  62. HART, LIANNE. (April 23, 1996). "MEDICINE : Texas Ebola Scare Is Over, but Coast Isn't Completely Clear". [[Los Angeles Times]].
  63. Schiermeier, Quirin. (January 1, 2004). "Primate lab faces closure threat over mistreatment charge". [[Nature (journal).
  64. (March 20, 2014). "Primate Abuse at Covance in Germany - Undercover TV". Alliance for Animals and the Environment.
  65. Gardner, Eriq. (January 20, 2014). "European Court Won't Lift Ban on Monkey Abuse Film". [[The Hollywood Reporter]].
  66. (May 18, 2005). "Animal-rights group alleges monkey abuse". [[United Press International]].
  67. Sinha, Vandana. (April 7, 2008). "Plan to lure animal testing firm Covance has PETA growling". [[American City Business Journals]].
  68. Buske, Jennifer. (August 3, 2008). "PETA Urges Withdrawal Of Support for Drug-Test Lab". [[The Washington Post]].
  69. (June 8, 2005). "Court report: Covance files suit vs. PETA; Scrushy says 'no plea bargain'". Bioworld.
  70. (January 17, 2006). "PETA: Cruel and Unusual". [[Competitive Enterprise Institute]].
  71. (July 26, 2005). "Covance Drops Appeal Of High Court Judgment, Allowing PETA Europe To Show Video Of Monkey Abuse Inside Its Lab". [[People for the Ethical Treatment of Animals]].
  72. (March 8, 2006). "McCartney protests against animal testing lab". [[Today (American TV program).
  73. "Covance officially opens Chandler lab". [[East Valley Tribune]].
  74. (June 9, 2011). "Inspection Report". [[United States Department of Agriculture]].
  75. (February 14, 2012). "Inspection Report". [[United States Department of Agriculture]].
  76. (March 2, 2012). "Inspection Report". [[United States Department of Agriculture]].
  77. (July 29, 2016). "Texas research facility fined for deaths of primates". [[Associated Press News]].
  78. Wahlberg, David. (November 13, 2023). "Labcorp fined after animal research violations in Madison". [[Wisconsin State Journal]].

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2015-mergers-and-acquisitionsanimal-testing-in-the-united-statescompanies-based-in-durham,-north-carolinacompanies-formerly-listed-on-the-new-york-stock-exchangecompanies-listed-on-the-nasdaqcontract-research-organizationscorning-inc.corporate-spin-offs