FAM114A2

FAM114A2 (chromosome 5 open reading frame 3) is a gene on chromosome 5 in humans that encodes a protein FAM114A2. The protein function is not well known. FAM114A2 is, however, highly conserved in mammals with homologs both in fungi and plants.

Species	Accession #	Identity
macaca mulatta	XM_001102467	78.1%
Pan troglodytes	XM_518045	89.7%
bos taurus	NP_001033166	85.6%
Pongo abelii	XM_002816109	87.8%
Mus musculus	NM_026342.3	79%
Callithrix jacchus	XP_002744467	94.7%

The FAM114A2 protein is 505 amino acids long with a molecular weight of 55.5 kdal and an isoelectric point of 4.66. It is predicted to stay in the nucleus after translation There is evidence that c5orf3 interacts with another protein of unknown function from chromosome 5, c5orf4 This protein is thought to include a P loop that suggests a role in ATP- and/or GTP-binding

The FAM114A2 gene is located on chromosome 5 (5q31-33). This gene has 14 exons spanning through its sequence. The coding sequence is 2886 base pairs with a 5’ UTR of 94 base pairs and a 3’ UTR of 1273 base pairs. It is expressed at high levels in most tissues of the human body. It is also highly expressed in tissues in the human brain

.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}body.skin-vector-2022 .mw-parser-output .reflist-columns-2{column-width:27em}body.skin-vector-2022 .mw-parser-output .reflist-columns-3{column-width:22.5em}.mw-parser-output .references[data-mw-group=upper-alpha]{list-style-type:upper-alpha}.mw-parser-output .references[data-mw-group=upper-roman]{list-style-type:upper-roman}.mw-parser-output .references[data-mw-group=lower-alpha]{list-style-type:lower-alpha}.mw-parser-output .references[data-mw-group=lower-greek]{list-style-type:lower-greek}.mw-parser-output .references[data-mw-group=lower-roman]{list-style-type:lower-roman}.mw-parser-output div.reflist-liststyle-upper-alpha .references{list-style-type:upper-alpha}.mw-parser-output div.reflist-liststyle-upper-roman .references{list-style-type:upper-roman}.mw-parser-output div.reflist-liststyle-lower-alpha .references{list-style-type:lower-alpha}.mw-parser-output div.reflist-liststyle-lower-greek .references{list-style-type:lower-greek}.mw-parser-output div.reflist-liststyle-lower-roman .references{list-style-type:lower-roman}

• Human FAM114A2 genome location and FAM114A2 gene details page in the UCSC Genome Browser.

.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}

.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}.mw-parser-output :not(p):not(.asbox)+style+.asbox,.mw-parser-output :not(p):not(.asbox)+link+.asbox{margin-top:3em}