Endecaphyllacin

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title: "Endecaphyllacin" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["triketones", "triterpenes"] topic_path: "general/triketones" source: "https://en.wikipedia.org/wiki/Endecaphyllacin" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

Endecaphyllacin is either of two similar compounds found in certain plants, such as Hemsleya endecaphylla.

  • Endecaphyllacin A, 2β-hydroxy-20,21,22,23,24,25,26,27-octanorcucurbita-5-ene-3,11,16-trione, . Crystallizes with 1 molecule of methanol as colorless prisms, mp 207-209 °C;
  • Endecaphyllacin B, 2-hydroxy-20,21,22,23,24,25,26,27-octanorcucurbita-1,5-dien-3,11,16-trione, . It is the aglycon of khekadaengoside L from Trichosanthes tricuspidata. Crystallizes from methanol as colorless prisms, mp 229-231 °C

Endecaphyllacins A and B can be extracted from the dried tubers of Hemsleya endecaphylla with methanol, at concentrations 150 mg/72 g and 20 mg/72 g.

References

References

  1. Jian-Chao Chen, Gao-Hong Zhang, Zhong-Quan Zhang, Ming-Hua Qiu, Yong-Tang Zheng, Liu-Meng Yang, Kai-Bei Yu (2008), "Octanorcucurbitane and Cucurbitane Triterpenoids from the Tubers of ''Hemsleya endecaphylla'' with HIV-1 Inhibitory Activity". ''J. Nat. Prod.'' volume 71, pages 153–155 {{doi. 10.1021/np0704396

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