DISC2

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Non-coding RNA in the species Homo sapiens

title: "DISC2" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["non-coding-rna"] description: "Non-coding RNA in the species Homo sapiens" topic_path: "general/non-coding-rna" source: "https://en.wikipedia.org/wiki/DISC2" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Non-coding RNA in the species Homo sapiens ::

In molecular biology, disrupted in schizophrenia 2 (non-protein coding), also known as DISC2, is a long non-coding RNA molecule. In humans, the DISC2 gene that produces the DISC2 RNA molecule is located on chromosome 1, at the breakpoint associated with the chromosomal translocation found in Schizophrenia. It is antisense to the DISC1 gene and may regulate the expression of DISC1. DISC2 may also contribute to other psychiatric disorders.

References

References

  1. (May 2000). "Disruption of two novel genes by a translocation co-segregating with schizophrenia". Human Molecular Genetics.
  2. (2004). "DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness". Annals of Medicine.
  3. (Nov 2004). "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder". American Journal of Human Genetics.

::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::

non-coding-rna