Diethylethanolamine
title: "Diethylethanolamine" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["diethylamino-compounds", "hydroxyethyl-compounds"] topic_path: "general/diethylamino-compounds" source: "https://en.wikipedia.org/wiki/Diethylethanolamine" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
|ImageFile = Diethylethanolamine.svg
|ImageFile_Ref =
|ImageSize = 160
|ImageName = Skeletal formula of diethylethanolamine
|PIN = 2-(Diethylamino)ethan-1-ol
|OtherNames = 2-(Diethylamino)ethanol
Diethylaminoethanol
2-Diethylaminoethanol
N,N-Diethyl-2-aminoethanol
N,N-Diethylethanolamine
Diethyl(2-hydroxyethyl)amine
(2-Hydroxyethyl)diethylamine
2-Diethylaminoethyl alcohol
2-Hydroxytriethylamine
|Section1={{Chembox Identifiers
|CASNo = 100-37-8
|CASNo_Ref =
|UNII_Ref =
|UNII = S6DL4M053U
|PubChem = 7497
|ChemSpiderID = 13842001
|ChemSpiderID_Ref =
|EINECS = 202-845-2
|UNNumber = 2686
|MeSHName = 2-diethylaminoethanol
|ChEBI = 52153
|ChEBI_Ref =
|ChEMBL = 1183
|ChEMBL_Ref =
|RTECS = KK5075000
|Beilstein = 741863
|SMILES = CCN(CC)CCO
|StdInChI = 1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
|StdInChI_Ref =
|StdInChIKey = BFSVOASYOCHEOV-UHFFFAOYSA-N
|StdInChIKey_Ref =
|Section2={{Chembox Properties
|C=6 | H=15 | N=1 | O=1
|Appearance = Colourless liquid
|Odor = Ammoniacal and irritating
|Density = 884 mg mL−1
|MeltingPtF = -94
|MeltingPt_ref =
|Solubility = miscible
|BoilingPtK = 434.2
|LogP = 0.769
|VaporPressure = 100 Pa (at 20 °C)
|RefractIndex = 1.441–1.442
|Section3={{Chembox Hazards
|GHSPictograms =
|GHSSignalWord = DANGER
|HPhrases =
|PPhrases =
|FlashPtC = 50
|ExploLimits = 1.4–11.7%
|LD50 =
|PEL = TWA 10 ppm (50 mg/m3) [skin]
|IDLH = 100 ppm
|REL = TWA 10 ppm (50 mg/m3) [skin]
|LC50 = 924 ppm (rat, 4 hr)
1027 ppm (mouse)
|Section4={{Chembox Related
|OtherFunction_label = alkanols
|OtherFunction =
|OtherCompounds = Diethylhydroxylamine
Diethylethanolamine (DEAE) is the organic compound with the molecular formula . A colorless liquid, is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine.
Applications
Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
Diethylethanolamine reacts with 4-aminobenzoic acid to make procaine.
DEAE is a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography.
it can decrease the surface tension of water when the temperature is increased.
Solutions of DEAE absorb carbon dioxide (CO2).
Preparation
Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.
:(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH It is also possible to prepare it by the nucleophilic substitution of diethylamine and 2-chloroethanol.
Safety
Diethylethanolamine is an irritant to the eyes, skin, and lungs. The Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health have set occupational exposure limits for workers handling the chemical at 10 ppm (50 mg/m3) over an eight-hour workday.
References
References
- {{PGCH. 0210
- {{IDLH. 100378. 2-Diethylaminoethanol
- (2017). "Experiments and model for the surface tension of DEAE-PZ and DEAE-MEA aqueous solutions". The Journal of Chemical Thermodynamics.
- (1999). "Kirk-Othmer Encyclopedia of Chemical Technology". John Wiley & Sons.
- W. W. Hartman. (1934). "β-Diethylaminoethyl Alcohol". Organic Syntheses.
- (2011-04-04). "NIOSH Pocket Guide to Chemical Hazards". CDC.
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