CPK coloring
Colour convention for differentiating atoms
title: "CPK coloring" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["color-codes", "molecular-modelling"] description: "Colour convention for differentiating atoms" topic_path: "general/color-codes" source: "https://en.wikipedia.org/wiki/CPK_coloring" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::summary Colour convention for differentiating atoms ::
::figure[src="https://upload.wikimedia.org/wikipedia/commons/6/66/proline_model.jpg" caption="A plastic [[ball-and-stick model]] of [[proline]]. These models usually comply with CPK coloring."] ::
In chemistry, the CPK coloring (for Corey–Pauling–Koltun) is a popular color convention for distinguishing atoms of different chemical elements in molecular models.
History
::figure[src="https://upload.wikimedia.org/wikipedia/commons/b/b3/Molecular_Model_of_Methane_Hofmann.jpg" caption="Hofmann's methane model"] ::
August Wilhelm von Hofmann was apparently the first to introduce molecular models into organic chemistry, following August Kekule's introduction of the theory of chemical structure in 1858, and Alexander Crum Brown's introduction of printed structural formulas in 1861. At a Friday Evening Discourse at London's Royal Institution on April 7, 1865, he displayed molecular models of simple organic substances such as methane, ethane, and methyl chloride, which he had had constructed from differently colored table croquet balls connected together with thin brass tubes. Hofmann's original colour scheme (carbon = black, hydrogen = white, nitrogen = blue, oxygen = red, chlorine = green, and sulphur = yellow) has evolved into the later color schemes.
In 1952, Corey and Pauling published a description of space-filling models of proteins and other biomolecules that they had been building at Caltech. Their models represented atoms by faceted hardwood balls, painted in different bright colors to indicate the respective chemical elements. Their color schema included
- White for hydrogen
- Black for carbon
- Sky blue for nitrogen
- Red for oxygen They also built smaller models using plastic balls with the same color schema.
In 1965 Koltun patented an improved version of the Corey and Pauling modeling technique. "CPK" stands for Corey-Pauling-Koltun. In his patent he mentions the following colors:
- White for hydrogen
- Black for carbon
- Blue for nitrogen
- Red for oxygen
- Deep yellow for sulfur
- Purple for phosphorus
- Light, medium, medium dark, and dark green for the halogens (F, Cl, Br, I)
- Silver for metals (Co, Fe, Ni, Cu)
Typical assignments
::figure[src="https://upload.wikimedia.org/wikipedia/commons/a/a1/Molymods.jpg" caption="A box of [[ball-and-stick model]] pieces colored to represent several of the common elements." alt="brightly colored plastic balls with holes in them."] ::
Typical CPK color assignments include: ::data[format=table]
| other elements | pink | |
|---|---|---|
| :: |
Several of the CPK colors refer mnemonically to colors of the pure elements or notable compound. For example, hydrogen is a colorless gas, carbon as charcoal, graphite or coke is black, sulfur powder is yellow, chlorine is a greenish gas, bromine is a dark red liquid, iodine in ether is violet, amorphous phosphorus is red, rust is dark orange-red, etc. For some colors, such as those of oxygen and nitrogen, the inspiration is less clear. Perhaps red for oxygen is inspired by the fact that oxygen is normally required for combustion or that the oxygen-bearing chemical in blood, hemoglobin, is bright red, and the blue for nitrogen by the fact that nitrogen is the main component of Earth's atmosphere, which appears to human eyes as being colored sky blue.
It is likely that the CPK colours were inspired by models in the nineteenth century. In 1865, August Wilhelm von Hofmann, in a talk at the Royal Institution in London, was using models made from croquet balls to illustrate valence, so he used the coloured balls available to him. (At the time, croquet was the most popular sport in England, so the balls were plentiful.) The essay "On the Combining Power of Atoms", in the 12th volume of Chemical News, states that "Hofmann, at a lecture given at the Royal Institution in April 1865 made use of croquet balls of different colours to represent various kinds of atoms (e.g. carbon black, hydrogen white, chlorine green, 'fiery' oxygen red, nitrogen blue)."
Modern variants
::figure[src="https://upload.wikimedia.org/wikipedia/commons/7/7f/CPK-coloring-periodic-table.svg" caption="Example of Jmol coloring"] ::
The following table shows colors assigned to each element by some popular software products.
- Column C is the original assignment by Corey and Pauling.
- Column K is that of Koltun's patent.
- Column J is the color scheme used by the molecular visualizer Jmol.
- Column R is the scheme used by Rasmol; when two colors are shown, the second one is valid for versions 2.7.3 and later.
- Column P consists of the colors in the PubChem database managed by the United States National Institute of Health.
All colors are approximate and may depend on the display hardware and viewing conditions.
::data[format=table]
References
References
- "Models".
- Ollis, W. D.. (1972). "Models and Molecules". Proceedings of the Royal Institution of Great Britain.
- (1953-08-01). "Molecular Models of Amino Acids, Peptides, and Proteins". Review of Scientific Instruments.
- Helmenstine, Todd. (2019-08-28). "Molecule Atom Colors - CPK Colors".
- "The conventions of colours of molecular models".
- Hofmann, August Wilhelm. (1865). "On the Combining Power of Atoms". Chemical News and Journal of Industrial Science.
- Maurice P. Crosland. (2004). "Historical Studies in the Language of Chemistry". Courier Corporation.
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