Complete Genomics
Chinese biotechnology company
title: "Complete Genomics" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["biotechnology-companies-of-the-united-states", "biotechnology-companies-established-in-2006", "genomics-companies", "companies-based-in-mountain-view,-california", "technology-companies-based-in-the-san-francisco-bay-area", "2006-establishments-in-california", "2013-mergers-and-acquisitions"] description: "Chinese biotechnology company" topic_path: "geography/united-states" source: "https://en.wikipedia.org/wiki/Complete_Genomics" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::summary Chinese biotechnology company ::
::data[format=table title="Infobox company"]
| Field | Value |
|---|---|
| name | Complete Genomics |
| type | Private |
| area_served | Worldwide |
| industry | Biotechnology |
| parent | MGI |
| homepage | |
| foundation | 2006 |
| location_city | San Jose, California |
| location_country | U.S. |
| :: |
| name = Complete Genomics | logo = | type = Private | traded_as = | founder = | area_served = Worldwide | key_people = | industry = Biotechnology | genre = | products = | services = | num_employees = | revenue = | operating_income = | net_income = | assets = | equity = | owner = | parent = MGI | divisions = | subsid = | homepage = | foundation = 2006 | location_city = San Jose, California | location_country = U.S. | location = | locations = | caption = | footnotes =
Complete Genomics is a life sciences company that has developed and commercialized a DNA sequencing platform for human genome sequencing and analysis. The company is a wholly owned subsidiary of MGI.
History
Complete Genomics was founded in June 2005 by Clifford Reid, Radoje (Rade) Drmanac, and John Curson. Clifford Reid was the chairman, president and chief executive officer of Complete Genomics before leaving in 2015 to set up Genos, a spinoff of Complete Genomics' consumer division.
In February 2009, Complete Genomics announced that it had sequenced its first human genome and submitted the resulting variant data to the National Center for Biotechnology Information database. In November 2009, Complete Genomics published sequence data for three human genomes in the journal Science.
The resulting data has supported research in diverse areas such as screening of embryos, |author=Winard R |date=2014 |title=In vitro screening of embryos by whole-genome sequencing: now, in the future or never? |journal=Hum Reprod |volume=29 |issue=4 |pages=842–851 |display-authors=etal |doi=10.1093/humrep/deu005 |pmid=24491297 |doi-access=free |author=Li H |date=2014 |title=Relationship estimation from whole-genome sequence data |journal=PLOS Genet |volume=10 |issue=1 |doi=10.1371/journal.pgen.1004144 |pmid=24497848 |pmc=3907355 |article-number=e1004144 |display-authors=etal |doi-access=free |author=Su S-Y |date=2012 |title=Detection of identity by descent using next-generation whole genome sequencing data |journal=BMC Bioinformatics |doi=10.1186/1471-2105-13-121 |pmid=22672699 |pmc=3403908 |volume=13 |article-number=121 |display-authors=etal |doi-access=free |author=Bundo M |date=2014 |title=Increased L1 retrotransposition in the neuronal genome in schizophrenia |journal=Neuron |volume=81 |issue=2 |pages=306–313 |doi=10.1016/j.neuron.2013.10.053 |pmid=24389010 |doi-access=free |author=Kai Y |date=2013 |title=Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs |journal=Twin Research and Human Genetics |volume=16 |issue=6 |pages=1026–1032 |display-authors=etal|doi=10.1017/thg.2013.73 |pmid=24182360 |doi-access=free |author=Wang K |date=2013 |title=Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement |journal=Genome Medicine |volume=5 |issue=7 |article-number=67 |doi=10.1186/gm471 |pmid=23889995 |display-authors=etal |pmc=3971341 |doi-access=free |author=Cui H |date=2013 |title=Eating disorder predisposition is associated with ESRRA and HDAC4 mutations |journal=J Clin Invest |volume=123 |issue=11 |pages=4706–4713 |doi=10.1172/jci71400 |display-authors=etal |pmid=24216484 |pmc=3809805}} Prader-Willi syndrome and autism, |author=Schaaf CP |date=2013 |title=Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism |journal=Nature Genetics |volume=45 |issue=11 |pages=1405–1408 |doi=10.1038/ng.2776 |pmid=24076603 |display-authors=etal|pmc=3819162 |author=Nishiguchi KM |date=2012 |title=Genes associated with retinitis pigmentosa and allied diseases are frequently mutated in the general population |journal=PLOS ONE |volume=7 |issue=7 |article-number=e41902 |doi=10.1371/journal.pone.0041902 |display-authors=etal|bibcode = 2012PLoSO...741902N |pmid=22848652 |pmc=3407128|doi-access=free |author=Ma Y |date=2012 |title=Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia |journal=Proc Natl Acad Sci USA |volume=110 |issue=18 |pages=7429–7433 |doi=10.1073/pnas.1221099110 |display-authors=etal|bibcode = 2013PNAS..110.7429M |pmid=23569245 |pmc=3645544|doi-access=free |author=Kiel MJ |date=2012 |title=Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma |journal=The Journal of Experimental Medicine |volume=209 |issue=9 |pages=1553–1565 |doi=10.1084/jem.20120910 |display-authors=etal |pmid=22891276 |pmc=3428949}} |author=Molenaar JJ |date=2012 |title=Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes |journal=Nature |volume=483 |issue=7391 |pages=589–593 |doi=10.1038/nature10910 |display-authors=etal|bibcode = 2012Natur.483..589M |pmid=22367537|doi-access=free |hdl=1765/57581 |hdl-access=free |author=Turajlic S|author-link=Samra Turajlic |date=2011 |title=Whole genome sequencing of matched primary and metastatic acral melanomas |journal=Genome Res |volume=22 |issue=2 |pages=196–207 |doi=10.1101/gr.125591.111 |display-authors=etal |pmid=22183965 |pmc=3266028}} |author=Yokoyama S |date=2011 |title=GA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma |journal=Nature |volume=480 |issue=7375 |pages=99–103 |doi=10.1038/nature10630 |pmid=22080950 |display-authors=etal|bibcode = 2011Natur.480...99Y |pmc=3266855 |author=Gilissen C |date=2014 |title=Genome sequencing identifies major causes of severe intellectual disability |journal=Nature |volume=511 |issue=7509 |pages=344–347 |doi=10.1038/nature13394 |pmid=24896178 |display-authors=etal|bibcode = 2014Natur.511..344G |s2cid=205238886 |hdl=2066/138095 |hdl-access=free
In 2016, Complete Genomics contributed over 184 phased human genomes to George Church's Personal Genome Project. In 2019, they published their new single-tube long fragment read (stLFR) technology, enabling the construction of long DNA molecules from short reads using a combinatorial process of DNA barcoding. It enables phasing, SV detection, scaffolding, and cost-effective diploid de novo genome assembly from second-generation sequencing technology.
In March 2013, Complete Genomics was acquired by BGI Group, a genomics services company in Shenzhen, Guangdong, China. After the acquisition, Complete Genomics moved to San Jose and in June 2018 became part of MGI. MGI was a subsidiary of BGI Group before it was spun out and listed on the Shanghai Stock Exchange in 2022.
References
References
- (13 June 2016). "Consumer Genomics Startup Genos Research Plans to Let Customers Explore, Share Their Data".
- (15 June 2023). "Complete Genomics Announces Updated Mission and New Partnerships on 18th Anniversary".
- Drmanac R. (November 2009). "Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays". Science.
- (2016-12-01). "The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes". GigaScience.
- (2019-05-01). "Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly". Genome Research.
- Specter, Michael (6 January 2014) [http://www.newyorker.com/magazine/2014/01/06/the-gene-factory The Gene Factory] {{Webarchive. link. (2014-10-28 The New Yorker, Retrieved 28 October 2014)
- brandonvd. "About Us".
- (18 April 2023). "Chinese genetics company targets US despite political tensions".
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