Co-tenidone

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title: "Co-tenidone" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["beta-blockers", "thiazides", "combination-antihypertensive-drugs"] description: "Combination medication" topic_path: "general/beta-blockers" source: "https://en.wikipedia.org/wiki/Co-tenidone" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Combination medication ::

| verifiedrevid = 443540052 | type = combo | component1 = Atenolol | class1 = Beta blocker | component2 = Chlortalidone | class2 = Thiazide diuretic | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = POM | legal_US = | legal_status = | routes_of_administration = Oral | CAS_number = | ATC_prefix = | ATC_suffix = | PubChem = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 151231 Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, carries an unacceptable risk of provoking type 2 diabetes at usual doses.

Formulation

Two strengths of co-tenidone are currently available in the UK:

• 50 mg atenolol and 12.5 mg chlortalidone, BAN of Co-tenidone 50/12.5
• 100 mg atenolol and 25 mg chlortalidone, BAN of Co-tenidone 100/25

References

• British National Formulary 54, September 2007

Footnotes

References

1. (2006-06-28). "NICE and BHS launch updated hypertension guideline". [[National Institute for Health and Clinical Excellence]].

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