CD7

CD7 (Cluster of Differentiation 7) is a protein that in humans is encoded by the CD7 gene.

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

• Cluster of differentiation
• DC-7

CD7 has been shown to interact with PIK3R1.

CD7 can be aberrantly expressed in refractory anaemia with excess blasts (RAEB) and may confer a worse prognosis. Also, a lack of CD7 expression could insinuate mycosis fungoides (MF) or Sezary syndrome (SS).

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• CD7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Human CD7 genome location and CD7 gene details page in the UCSC Genome Browser.

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