Bufanolide

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title: "Bufanolide" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["bufanolides"] topic_path: "general/bufanolides" source: "https://en.wikipedia.org/wiki/Bufanolide" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

| verifiedrevid = | ImageFile = Bufanolide structure.png | ImageSize = 200px | IUPACName = 5ξ-Bufanolide | SystematicName = (5R)-5-[(1R,3aR,3bR,5aΞ,9aS,9bS,11aS)-9a,11a-Dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]oxan-2-one | OtherNames = |Section1={{Chembox Identifiers | SMILES1 = C[C@]12CC[C@H]3C@HCCC5[C@@]3(CCCC5)C | StdInChI_Ref = | StdInChI = 1S/C24H38O2/c1-23-13-4-3-5-17(23)7-8-18-20-10-9-19(16-6-11-22(25)26-15-16)24(20,2)14-12-21(18)23/h16-21H,3-15H2,1-2H3/t16-,17?,18-,19+,20+,21-,23-,24+/m0/s1 | StdInChIKey_Ref = | StdInChIKey = PXOHOSHERMSUCD-YQMMVUDVSA-N | CASNo_Ref = | CASNo = 29565-35-3 | PubChem = 115047 | ChemSpiderID_Ref = | ChemSpiderID = 102963 | SMILES = CC12CCCCC1CCC3C2CCC4(C3CCC4C5CCC(=O)OC5)C |Section2={{Chembox Properties | Formula=C24H38O2 | MolarMass=358.28718 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = Bufanolide is a C24 steroid and, indirectly, a parent structure of bufadienolide. Its derivatives was found in Bufo and Scilla, as an aglycone of cardiac glycosides and is usually toxic.

References

References

  1. Tao Song, Yuanyuan Zhang, Qiongtao Song, Xue Han, Shengjiang Guan, Xuan Zhang, Xi Chu, Fenghua Zhang, Jianping Zhang, Li Chu. (2017-08-16). "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K + currents expressed in HEK293 cells". Fundamental & Clinical Pharmacology.

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bufanolides