Antithrombotic

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An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi). Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases.

An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi). Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases.

Different antithrombotics affect different blood clotting processes:

  • Antiplatelet drugs limit the migration or aggregation of platelets.

  • Anticoagulants limit the ability of the blood to clot.

  • Thrombolytic drugs act to dissolve clots after they have formed.

  • Direct Xa inhibitor

  • Warfarin

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  • Antithrombotic Therapy / American Society of Hematology

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