Acotiamide

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Column 1
Acofide, others
YM-443, Z-338
By mouth
.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}A03FA10 (WHO) QA03FA10 (WHO)
JP: Rx-only
84.21–85.95%
UGT1A8 and 1A9 (major)
10.9–21.7 hours
Feces (92.7%), urine (5.3%)
IUPAC name
N-{2-[bis(1-Methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide
185106-16-5 N
5282338
4445505 Y
D42OWK5383
D08838 N
ChEMBL2107723 N
DTXSID40870163
C21H30N4O5S
450.55 g·mol−1
Interactive image
SMILES
O=C(Nc1nc(C(=O)NCCN(C(C)C)C(C)C)cs1)c2cc(OC)c(OC)cc2O
InChI
InChI=1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27) YKey:TWHZNAUBXFZMCA-UHFFFAOYSA-N Y
.mw-parser-output .nobold{font-weight:normal} NY (what is this?)  (verify)

Acotiamide, sold under the brand names Acofide, and Dyspevict is a medication manufactured and approved in Japan and Russia for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.

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