5-HO-DiPT
5-HO-DiPT, also known as 5-hydroxy-N,N-di-iso-propyltryptamine, is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.
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| Column 1 |
|---|
| 5-OH-DiPT; 5-Hydroxy-N,N-diisopropyltryptamine |
| IUPAC name |
| 3-(2-(diisopropylamino)ethyl)-1H-indol-5-ol |
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| 71360804 |
| 29358411 |
| G7I3OBF3XM |
| DTXSID80784573 |
| C16H24N2O |
| 260.381 g·mol−1 |
| Interactive image |
| SMILES |
| CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C |
| InChI |
| InChI=1S/C16H24N2O/c1-11(2)18(12(3)4)8-7-13-10-17-16-6-5-14(19)9-15(13)16/h5-6,9-12,17,19H,7-8H2,1-4H3Key:HWOLNTJLIUHEOG-UHFFFAOYSA-N |
5-HO-DiPT, also known as 5-hydroxy-N,N-di-iso-propyltryptamine, is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.
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Analogues of 5-HO-DiPT include diisopropyltryptamine (DiPT), 4-HO-DiPT (iprocin), 4-AcO-DiPT (ipracetin), 5-MeO-DiPT, bufotenin (5-HO-DMT), 5-AcO-DMT, 5-HO-MET, 5-HO-DET, 5-HO-DPT, and α-methylserotonin (5-HO-AMT), among others.
- Substituted tryptamine
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- 5-HO-DiPT - Isomer Design