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4-MeS-DMT

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4-MeS-DMT, or 4-SMe-DMT, also known as 4-methylthio-N,N-dimethyltryptamine, is a serotonin receptor modulator and possible psychedelic drug of the tryptamine family related to psilocin. It is the 4-methylthio derivative of psilocin (4-HO-DMT) and is an analogue of 4-MeO-DMT. The drug's properties and effects in humans are unknown. It shows affinity for serotonin receptors. 4-MeS-DMT produces psychedelic-like behavioral effects in animals, for instance generalization with 5-MeO-DMT in rodent drug discrimination tests, though is less potent than 5-MeS-DMT or 4-MeO-DMT. The chemical synthesis of 4-MeS-DMT has been described. 4-MeS-DMT was first described in the scientific literature by Richard Glennon and colleagues in 1982. Subsequently, it was briefly described by Alexander Shulgin in his book TiHKAL (Tryptamines I Have Known and Loved) in 1997.